Key observations are that: children who died were younger than those still alive at 1 year; kwashiorkor (oedematous malnutrition) was the dominant type of SAM but risk of death was lower than in non-oedematous SAM; children who were more malnourished (lower z-scores); at baseline were more likely to die; HIV was prevalent and HIV-associated mortality was high, especially with advanced disease (as indicated by low CD4 count); disability - mostly neurodisability such as cerebral palsy - was common and deaths among disabled children were high. The gene discussed is CD4; the disease is cerebral palsy.