TNF and rheumatoid arthritis: Other potential candidates (for clinical treatment) include drugs indicated for the treatment of rheumatoid arthritis and other inflammatory diseases, such as traditional nonsteroidal anti-inflammatory drugs (NSAIDs), selective cyclooxygenase (COX) inhibitors (e.g., celecoxib), tumor necrosis factor (TNF) antagonists (e.g., etanercept, infliximab, adalimumab), and interleukin-1 antagonists (e.g., anakinra) [73].