ERVW-1 and melanoma: HML-2 Pol, Gag and Env,52 and accessory proteins Rec and Np9 have also been detected in melanoma.18,51 Further studies sought to predict the prognostic value of HERV-K in melanoma and found that HERV-K was a statistically significant marker of acrolentiginous, mucosal and uveal melanoma.