High LAT1 expression was associated with poorer prognosis in patients with negative (P = 0.0556) and positive (P = 0.0009) surgical margins (data not shown) and in patients with negative (P = 0.0004) and positive (P = 0.1546) for lymph node metastasis (data not shown), indicating that high LAT1 expression is an individual prognostic factor. This evidence concerns the gene LAT and metastatic malignant neoplasm in the lymph nodes.