For example, one of these inhibitors, JPH203 (KYT-0353), significantly inhibited the growth of human colon cancer cells in vitro and in vivo 18, and 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, a second inhibitor, reduced the viability of lung cancer cells 19, suggesting that LAT1 inhibitors may be clinically useful as cancer chemotherapy. This evidence concerns the gene LAT and cancer.