AKT1 and renal cell carcinoma: Corroborating our work on HTLV-1, Gurova and colleagues went on to show that 9AA targets two important stress-responsive pathways, NF-κB and p53, in Renal cell carcinoma (RCC) cell lines, as well as the prosurvival AKT/mammalian target of rapamycin (mTOR) pathway [22,24,46].