CCL2 and neoplasm: Different C-C motif ligand-chemokines (CCL) and C-X-C motif ligand chemokines (CXCL), such as CCL2, CCL7, CXCL1 and CXCL6, are also potent stimulators of pro-malignant features, such as tumor cell proliferation, migration and invasion, as well as angiogenesis.