Thorsteinsson, et al. studied 37 patients with stage II and III colon cancer; TLR4 expression was significantly higher in stage III tumors than stage II for two of the four TLR4 probes (Medium, p = 0.061 and Long2, p = 0.092) (GSE31595) [24]. Here, TLR4 is linked to malignant colon neoplasm.