TLR4 and cancer: Tumor fractions consisting of a mixture of adenoma and carcinoma, earlier stages of cancer, and carcinomas with lymph node metastasis, all had lower TLR4 expression than adenomas with low-grade dysplasia (coef = −1.81, p = 0.043; coef = −1.56, p = 0.058; and coef = −1.27, p = 0.05, respectively) (GSE12225).