Further studies are needed to investigate why naïve CD4+ T cells from patients with patients with active BD developed into more Th17 cells and whether these polarized Th17 cells, in addition to expressing more IL-17, produced a higher level of other cytokines, such as IFN-γ, GM-CSF, IL-2 and IL-10. The gene discussed is IL2; the disease is Behcet disease.