SOD1 and Hyperglycemia: Specifically, diaphragm specific force generation (for example, 80 Hz force) was 26.4 ± 0.9, 15.4 ± 0.9, 24.0 ± 1.5 and 14.9 ± 0.9 N/cm2 for control, two week hyperglycemia, two week hyperglycemia + PEG-SOD and two week hyperglycemia + denatured PEG-SOD groups, respectively (P <0.001).