Two SNPs showed significant association with an increased CML risk in the recessive model: ARHGAP26_rs187729 T > C and IRF8_rs10514611 C > T with adjusted OR (95% CI) = 1.63 (1.08-2.47), p = 0.0213 (corrected p = 0.123) and 2.4 (1.12-5.15), p = 0.0246 (corrected p = 0.123), respectively. This evidence concerns the gene IRF8 and chronic myelogenous leukemia, BCR-ABL1 positive.