However, the FOXO4 staining in nontumorous tissues (NT) was consistently stronger than that of the GC samples, and there was a significant difference between the staining results of the GC and NT samples (Figure 1A2) (P < 0.05).We next measured the FOXO4 level in an independent tissue microarray panel containing 40 primary GCs and corresponding lymph node metastasis specimens. The gene discussed is FOXO4; the disease is metastatic malignant neoplasm in the lymph nodes.