In patients with eGFR < 60 ml/minute/1.73 m2, plasma levels of Ang-2 (7,374 ± 6,357 pg/ml, n = 10 vs. 2,945 ± 1,314 pg/ml, n = 13; P = 0.023) and TM (7.84 ± 1.95 ng/ml, n = 10 vs. 5.99 ± 1.32 ng/ml, n = 13; P =0.013) were increased in patients with AKI compared with those without (Figure 1). This evidence concerns the gene ANGPT2 and acute kidney injury.