Compared with patients without AKI, patients with AKI had higher incidence of hypertension (84.6 vs. 44.5%, P = 0.008) and coronary artery disease history (53.8 vs. 10.9%, P < 0.001), increased peripheral blood leukocyte count (15,954 ± 8,647 vs. 11,160 ± 3,646/ml, P <0.001), plasma levels of hsCRP (44.86 ± 63.82 vs. 13.44 ± 28.38 mg/l, P = 0.001), Ang-2 (6,338.28 ± 5,862.77 vs. 2,412.03 ± 1,256.58 pg/ml, P = 0.033) and sTM (7.6 ± 2.26 vs. 5.34 ± 2.0 ng/ml, P < 0.001). The gene discussed is ANGPT2; the disease is acute kidney injury.