Consistent with HEY cell line, addition of CYT387 resulted in the inhibition of phosphorylation of JAK2 and STAT3 in paclitaxel-induced ascites-derived tumor cells (Ascites 9–11, Table 1), while the expression of T-JAK2 and T-STAT3 remained unchanged (Figure 7A and B). The gene discussed is JAK2; the disease is neoplasm.