Further data validated that the inhibition of HBXIP by siRNA obviously resulted in the reduction of tumor formation and depressed the growth of LO2-X-S cells in mice (n = 5, each group), meanwhile, the expression levels of HBXIP in the tumor tissues from mice were correspondence to the growth of tumor by western blotting (Figure 6E-G). Here, LAMTOR5 is linked to neoplasm.