A single-oral dose of P450 was highly efficacious, resulting in a ERR and WRR of almost 100% for both low (ERR: 98.3 [95% CI: 92.7; 100]; WRR: 99.0% [95% CI: 97.7; 99.9]) and high intensity infections (ERR: 98.9 [95% CI: 95.5; 99.9]; WRR: 97.4%% [95% CI: 94.3; 99.7]). The gene discussed is CYP2B6; the disease is infection.