CDKN1A and neoplasm: In addition, Sui68/EGFP exhibited a significantly elevated level of tumorigenesis (Sui68/EGFP 14/14 vs. Sui68/p21 8/14, P = 0.016), and Sui68/EGFP exhibited a larger tumor volume than Sui68/p21 on day 15 (Sui68/EGFP, 507.0 ± 83.5 mm3 vs. Sui68/p21, 276.5 ± 95.0 mm3; P = 0.0036*) (Figure 8D).