Thus, although to our knowledge our studies are the first to show these aspects in molluscs, it is not surprisingly that similar conclusions are drawn with increasing frequency in studies linking oxidative stress related PLA2 activation with cognitive impairment, neuronal dysfunction and disease not only in other, non-molluscan, invertebrate species but also in mammals and humans[12,16,34-38]. Here, PLA2G6 is linked to Cognitive impairment.