siRNA-mediated knockdown of DCLK1 in the AsPC-1 pancreatic cancer cell line results in inhibition of epithelial-to-mesenchymal transition (EMT) and oncogenic targets through induction of tumor suppressor miRNAs let-7a and miR-144 and EMT-inhibitor miR-200a[8]. Here, DCLK1 is linked to familial pancreatic carcinoma.