IFNG and tuberculosis: In the last years, interferon–γ (IFN-γ) release assays (IGRAs), the Quantiferon-TB Gold in Tube (QFN-G-IT) (QIAGEN, Düsseldorf, Germany), and the T-SPOT.TB (Oxford Immunotec Limited, Abingdon, UK), have been introduced into clinical practice as laboratory methods for the immune-diagnosis of latent TB infection (LTBI) [5].