Elevated CRP levels have been reported in dogs after surgical trauma [14], during infections including leishmaniasis [15], ehrlichiosis [16], babesiosis [5], leptospirosis [17], bordetellosis [18], parvovirus infection [17] and pyometra [19], and with noninfectious conditions including neoplasia [20], autoimmune disorders [20], acute pancreatitis [21], inflammatory bowel disease [22] and cardiac valvular disease [23]. This evidence concerns the gene CRP and pyometritis.