The NKG2DLs MICA and MICB play an important role in the NK cell-mediated lysis of cancer cells [21]; therefore, we determined the effect of VPA on the expression of MICA and MICB mRNA in the human pancreatic cancer cell lines PANC-1, MIA PaCa-2, and BxPC-3. The gene discussed is MICA; the disease is familial pancreatic carcinoma.