Other cellular processes and molecular pathways that may be involved in the anti-cancer effects of selenium are the induction of phase II conjugating enzymes that detoxify carcinogens, enhancement of the immune response, an increase in tumor-suppressor protein p53, inactivation of protein kinase C (PKC), alterations in DNA methylation, blockage of the cell cycle to allow DNA repair, induction of apoptosis in cancer cells and inhibition of angiogenesis [11]. Here, PRRT2 is linked to cancer.