MMP-10 (also known as stromelysin 2) is generally limited to epithelial cells [3] and can target pro-MMP-1, -7, -8, -9, -13, collagen type III, IV, V, gelatin, elastin, fibronectin, proteoglycans and laminin [4], activities that have been shown to promote tumor cell invasion [5]. The gene discussed is ELN; the disease is neoplasm.