In contrast, GDM patients presented several genes that were induced compared to T2D, including immune response genes (CXCL10, CXCR4, CD46, CCL3L3, IL1B, IL1A, NFKBIZ, IL27, C1QA, CD83, C1QB, HIF1A, DEFA4, DEFA3, KIR2DL4, CXCL1, CCL3, TNF, CCR1, CXCL3, CXCL2, CCL4, CCL23, CCL20, IL6, CR2, IL8, IL1RN STAT3, CD55) and genes involved in the response to hormone stimulus (PTGS2, LDLR, PGF, PDGFA, PTGS1, NOS3, ADAM9, EGR2, SOCS2, SOCS3, RXRA, ADIPOR1, GAL, JUNB, C1QB, RETN, ADM, SORT1, CAV2, CAV1, TNF, GRB2, ERBB3, GNG11, BCL2L1, PIK3R1, IL6, IL1RN, STAT1, STAT3, CDKN1A, BMP7, IGFBP2). The gene discussed is HIF1A; the disease is gestational diabetes.