Notably, a strong decrease in IL-6 was found in 16/17 CF patients during AB therapy (P = 0.0059, Table 1 and Figure 3C and 3D) and also in MMP9 and RANTES, where the median values declined two-fold and 10-fold, respectively (Table 1, Figure 3A and 3B and Additional file 1: Figure S1). The gene discussed is MMP9; the disease is cystic fibrosis.