When stratified on basis of tobacco habits, Gemin3 and mir-34b reduced risk of leukoplakia among smokers too [p = 0.05 and 0.04 respectively] while minor allele homozygous genotype at mir-29a increased risk of leukoplakia significantly [p = 0.05] among chewers. This evidence concerns the gene DDX20 and Oral leukoplakia.