Vasohibin-2 (VASH2) is mainly expressed by infiltrating bone marrow-derived mononuclear cells at the angiogenic-sprouting front[16-20], and the expression of VASH2 in human serous ovarian adenocarcinoma and hepatocellular carcinoma accelerates tumor growth by promoting angiogenesis[21,22]. Here, VASH2 is linked to hepatocellular carcinoma.