The mRNA levels of stathmin were 0.3 ± 0.12 (mean ± SD) (range, 0.2 ~ 0.5) in normal liver, 0.5 ± 0.61 (0.1 ~ 2.1) in liver cirrhosis, 0.8 ± 0.57 (0.1 ~ 2.0) in low-grade DNs, 1.5 ± 1.29 (0.1 ~ 4.7) in high-grade DNs, and 2.3 ± 1.95 (0.4 ~ 7.0) in HCC. Here, STMN1 is linked to cirrhosis of liver.