In a previous study, the expression of five selected miRNAs in a group of glatiramer acetate and interferon-beta treated MS patients, from peripheral blood mononuclear cell, has been evaluated to detect a potential impact of immuno-modulatory therapy on deregulated miRNAs [26]: however, miRNAs expression did not differ between treatment-naıve and IFN-beta treated RRMS patients. Here, IFNB1 is linked to relapsing-remitting multiple sclerosis.