NR3C1 and plasma cell myeloma: Even as the expression or mutational status of single genes are shown to influence response to specific myeloma treatments, e.g. expression levels of the glucocorticoid receptor gene NR3C1 and thalidomide [29], ‘treatment-independent’ risk-stratification assays such as GEP70 are likely to remain an important component in providing tailored treatment plans and ensuring optional outcomes.