CXCL8 and bullous pemphigoid: Some studies have found that interleukin 8 (IL-8) plays an important role not only in inflammatory acne vulgaris [12], but also in psoriasis and bullous pemphigoid [13,14], so compound glycyrrhizin might block production of some cytokines, including IL-8, in the treatment of erythrodermic psoriasis and bullous pemphigoid lesions.