To examine the prognostic role of KRAS mutation independent of BRAF mutation, within 1067 BRAF-wild-type cases (excluding BRAF mutants), we compared KRAS-mutated cancers to cases with wild-type KRAS in all four codons 12, 13, 61 and 146 (Additional file2: Table S2). The gene discussed is BRAF; the disease is cancer.