As expected, MDA-MB-468shAhR (Figure 4A) and Cal51shAhR (Figure 4C) were sensitive to AF when endogenous levels of AhR protein are present, with GI50 ranges for AF of 13.1nM–17.3nM and 10.9nM–25.4nM, respectively. The gene discussed is AHR; the disease is atrial fibrillation.