This elevated anxiety level was manifested as a significant reduction in percentage of open arm duration (48.9% reduction; vehicle: 29.16 ± 3.08%, CORT: 14.89 ± 2.50%; P < 0.05; Figure 3A-12d) and number of open arm entry (55.2% reduction; vehicle: 23.90 ± 3.80, CORT: 10.70 ± 1.95; P < 0.05; Figure 3B-12d). This evidence concerns the gene CORT and Anxiety.