For example, it was reported that the genotype AA at the SNP rs2032582 in the ABCB1 gene is associated with an increased required dose of antipsychotics in patients with schizophrenia [20], while CC and AC genotypes are associated with decreased responsiveness to paroxetine in patients with depression compared with the AA genotype [21,22]. Here, ABCB1 is linked to depressive disorder.