For example, how does the specification of Chopin’s chronic respiratory illness to several different diseases, tuberculosis, COPD, cystic fibrosis, alpha-1 antitrypsin deficiency, make any significant difference in understanding Chopin’s artistic accomplishment, music style, music performance, and Chopin’s biography overall? This evidence concerns the gene SERPINA1 and hyperinsulinemic hypoglycemia, familial, 4.