Cytokine array analysis of culture supernatant from USP18 overexpression and knockdown B16-OVA tumor cells did not show significant differences (Additional file1: Figure S5A), but analysis of a chemokine panel showed that in B16-OVA-USP18 cells, increased secretion of chemokines related to NK cell migration was observed (Additional file1: Figure S5B). The gene discussed is USP18; the disease is neoplasm.