To study the effects of CIP2A on the malignant growth of NPC cells, we transfected siCIP2A or scrambled control siRNA into CNE-2 and SUNE-1 cells and found that CIP2A depletion significantly suppressed the anchorage-independent growth of both CNE-2 and SUNE-1 cells (all P < 0.05, Figure 3E). The gene discussed is CIP2A; the disease is nasopharyngeal carcinoma.