TNFAIP3 and rheumatoid arthritis: To identify the role of the polymorphisms in the TNFAIP3 gene on the risk of RA in Asian population, in the present study, we describe a case–control study of 1280 RA cases and 1280 controls from northern Chinese han population; stratified analyses were carried on by gender and age; we also explored the interaction between genetic polymorphisms in the development of RA.