The high proportion of patients who were responders for RA, CD, and psoriasis provide some support for the effectiveness of anti-TNF agents at 12 months which parallels the results of other studies (Breedveld et al., 2006; Colombel et al., 2010; Colombel et al., 2007; Kameda et al., 2010; Sandborn et al., 2007b; Weinblatt et al., 2003; Weinblatt et al., 1999). The gene discussed is TNF; the disease is rheumatoid arthritis.