OPTN and open-angle glaucoma: Mendelian forms of open angle glaucoma have been associated with mutations in myocilin (MYOC) [4], optineurin (OPTN) [5], WD repeat domain36 (WDR36) [6], neurotrophin 4 (NTF4) [7], TANK binding kinase 1 (TBK1) [8], and ankyrin binding kinase 10 (ASB10) [9].