For the genotypic frequencies, the mutant homozygous genotypes of rs2032582 and rs1045642 (2677TT and 3435TT) in the ABCB1 gene were significantly associated with reduced risks of developing pancreatic cancer in the whole study population and the European American subgroup (Tables 2 and 3, P = 0.015, OR = 0.29 and P = 0.013, OR = 0.35, resp., for the whole study population; P = 0.043, OR = 0.34 and P = 0.033, OR = 0.39, resp., for the European Americans). The gene discussed is ABCB1; the disease is familial pancreatic carcinoma.