However, the diagnostic performance of suPAR was not superior compared to CRP either for detecting infection (AUC = 0.905 (95% CI: 0.834–0.976), P < 0.001) or sepsis (AUC = 0.858 (95% CI: 0.714–1.000), P < 0.001), whereas it was almost equal compared to WBC and ANC for detecting infection (AUC = 0.787 (95% CI: 0.634–0.940), P = 0.001, and AUC = 0.820 (95% CI: 0.676–0.963), P < 0.001, resp). This evidence concerns the gene CRP and Sepsis.