Because the ALDH2 Lys487 allele is more prevalent in Asian populations (i.e., Japanese, Chinese, and Koreans) (Eng et al. 2007), and ALDH2 is hypothesized to impact the risk associated with alcohol for all cancers, studies should account for the presence of this allele when assessing the risk relationship between alcohol consumption and the development of any form of cancer. The gene discussed is ALDH2; the disease is cancer.