Furthermore, BAFF and its receptors are highly expressed in reactive lymphoid tissues and B-cell lymphomas, including diffuse large B-cell lymphoma (DLBCL), primary central nervous system lymphoma (PCNSL), mantle cell lymphoma (MCL), marginal zone B-cell lymphoma (MZBCL) and plasma cell myeloma (PCM). This evidence concerns the gene TNFSF13B and B-cell non-Hodgkin lymphoma.