DDR2 and squamous cell lung carcinoma: In contrast, squamous cell carcinoma of the lung is commonly associated with mutations in the NFE2L2/KEAP-axis [26] and often harbors targetable alterations of FGFR1 [27] and in fewer cases mutations in DDR2. Interestingly, DDR2-transformed cell lines maintain SRC phosphorylation and are sensitive to Dasatinib [28], proved by the response in squamous cell lung cancer patients [29].