DRD1 and alcohol abuse: In another study, Kim et al. [55] found that the severity of the alcohol-related problem as measured by the Alcohol Use Disorders Identification Test in a gene dose-dependent manner, was significantly associated with one 5′ UTR polymorphism in the DRD1 (DRD1-48A>G) gene; 24.37 (±8.19) among patients with −48A/A genotype, 22.37 (±9.49) among those with −48A/G genotype, and 17.38 (±8.28) among those with −48G/G genotype (P = 0.002).