CDH1 and pancreatic adenocarcinoma: As shown in Fig. 4, reduction in the expression of E-Cadherin was not statistically significant in the pancreatic adenocarcinoma, possibly due to the normal levels of expression in the duct and endothelial cells, which hindered the differences between the exocrine pancreas and tumor mass (Fig. 3D; supplementary material Fig. S3D′).