In previous studies we have demonstrated the influence of sialic acid determinants in cell-ECM adhesion and in migratory processes of various human cancer models, including gastric cancer cells [49], [50], and in pancreatic Capan-1 and MDAPanc-28 cell lines and their stably ST3Gal III transfected clones, C31 and M34 [25], [31]. This evidence concerns the gene ST3GAL3 and cancer.