AGT and type 1 diabetes mellitus: Yousif et al. [5, 6] and Pernomian et al. [8, 9] showed that type I-diabetes enhances the vasocontractile response evoked by angiotensin II [5, 6, 8, 9], which damages vascular function and contributes with atherogenesis by affecting both the vascular tone and the progression of vascular inflammation [10].